QuTEM extracellular vesicles

Extracellular vesicles

Extracellular vesicles (EVs), a broad term encompassing vesicles secreted by various cells, have emerged as promising drug carriers in gene therapies and vaccines. The composition of EV products can be influenced by factors like their cellular origin, manufacturing, and purification processes. Characterizing such products is challenging, but a visualization method with high resolution proves invaluable.  

Transmission Electron Microscopy (TEM) emerges as a reliable tool in this regard. It enables the identification of intact particles and analysis of size distribution and encapsulation efficiency, offering insights into product bioactivity. Moreover, TEM facilitates the monitoring of integrity, purity, and aggregation of EVs during manufacturing for lot comparison and stability studies.  


At QuTEM, we generally offer the following analyses for EVs.

Monitor the quality of EVs throughout the manufacturing process


Example report

Download an example report that includes:

  • Analysis of an exosome sample by cryoTEM

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