Learning center
method
New approaches to aggregation analysis by CryoTEM
Particle aggregation is a critical attribute across biologics, viral vectors, and nanoparticle-based systems. Even low levels of aggregation may influence product stability, biological activity, immunogenicity risk, and batch consistency.
Conventional b...
Peer-reviewed paper
research paper
AAV Vector Characterization with Quantitative TEM
Accurate characterization of AAV vector content is a critical quality attribute in gene therapy development and manufacturing. In this study, we validated Quantitative Transmission Electron Microscopy (QuTEM) as a robust method for single-particle class...
lentiviral vectors
Webinar
A new approach to AAV aggregation analysis
Check our recorded webinar on A new approach to AAV aggregation analysis !
In this webinar, our Chief Operating Officer, Rickard Nordström, discusses how TEM serves as a powerful tool for aggregation analysis and shares insights on our newly develop me...
AAV
genome length
vector content
White paper
White paper – AAV Genome Length Determination
This white paper presents QuTEM’s advanced analysis, offering precise characterization of for (AAV) capsids. Our validated platform leverages cryo-TEM imaging and density measurements to distinguish and quantify empty , partially filled, filled...
lentiviral vectors
Webinar
TEM Analysis of Lentivirus for Quality Control
Check our recorded webinar on TEM Analysis of Lentivirus for Quality Control!
In this video, Mathieu Colomb-Delsuc. Senior Scientist at QuTEM, discusses how TEM serves as a powerful tool for analyzing critical quality attributes of lentivirus In this we...