Learning center - TEM Resources
Explore QuTEM's TEM resources: a growing library of webinars, white papers and documents on the use of TEM and cryoTEM for nanoparticle analysis and quality control.
AAV
Aggregation
method
New approaches to aggregation analysis by CryoTEM
Particle aggregation is a critical attribute across biologics, viral vectors, and nanoparticle-based systems. Even low levels of aggregation may influence product stability, biological activity, immunogenicity risk, and batch consistency.
Conventional b...
AAV
Peer-reviewed paper
research paper
AAV Vector Characterization with Quantitative TEM
Accurate characterization of AAV vector content is a critical quality attribute in gene therapy development and manufacturing. In this study, we validated Quantitative Transmission Electron Microscopy (QuTEM) as a robust method for single-particle class...
AAV
Webinar
A new approach to AAV aggregation analysis
Check our recorded webinar on A new approach to AAV aggregation analysis !
In this webinar, our Chief Operating Officer, Rickard Nordström, discusses how TEM serves as a powerful tool for aggregation analysis and shares insights on our newly develop me...
AAV
genome length
vector content
White paper
White paper – AAV Genome Length Determination
This white paper presents QuTEM’s advanced analysis, offering precise characterization of for (AAV) capsids. Our validated platform leverages cryo-TEM imaging and density measurements to distinguish and quantify empty , partially filled, filled...
AAV
genome length
vector content
Webinar
White paper
TEM analysis of AAVs for quality control
Recorded webinar
Genome length determination
In this webinar, our COO, Rickard Nordström dived into the technical aspects of our latest method (Generation 3) for determining both the full-to-empty ratio and genome length of AAVs. With this advanc...
general service webinar
Webinar
Characterization of pharmaceutical nanoparticles
During the webinar, our CEO, Josefina Nilsson, introduced QuTEM’s services and TEM as a comprehensive assay. TEM provides vital insights into critical quality attributes such as purity, integrity, aggregation, size, circularity, and vector content...