Webinar – A new approach to AAV aggregation analysis

Check our recorded webinar on A new approach to AAV aggregation analysis !

In this webinar, our Chief Operating Officer, Rickard Nordström, discusses how TEM serves as a powerful tool for aggregation analysis and shares insights on our newly develop method helps to gain information on aggregation.

Two distinct approaches are demonstrated:
- A classification approach where aggregates and individual particles are directly segmented on the image, giving direct insights on the aggregation populations present in the specimen.
- A newly developed statistical approach, where the distance from each particle to its nearest neighbors is measured and compared to a theoretical value to identify true aggregation events, providing objective results.

02:17 - Introduction

03:17 - About QuTEM

09:09 - TEM for quality control

11:06 - Vector content and genome length analysis

17:13 - Case study

21:12 - Aggregation analysis

30:35 - Take home message

33:40 - Questions