During the webinar, our CEO, Josefina Nilsson, introduced QuTEM's services and TEM as a comprehensive assay. TEM provides vital insights into critical quality attributes such as purity, integrity, aggregation, size, circularity, and vector content. These attributes are analyzed for a variety of pharmaceutical vectors, including AAVs, adenoviral vectors, liposomes, lentiviral vectors, LNPs, and more.
Characterization of pharmaceutical nanoparticles
Related contents
AAV
genome length
vector content
Document
Webinar
TEM analysis of AAVs for quality control
Recorded webinar
Genome length determination
In this webinar, our COO, Rickard Nordström dived into the technical aspects of our latest method (Generation 3) for determining both the full-to-empty ratio and genome length of AAVs. With this advanc...
AAV
Aggregation
Genome length
Integrity
Morphological assessment
Purity
Size
Vector content
AAV
Adeno-associated virus (AAV)-based gene therapies have shown great promise in clinical trials, offering hope for treating a variety of genetic disorders. The efficacy of these therapies depends, among many factors, on the ratio of full to empty capsids,...
lentiviral vectors
Aggregation
Genome length
Integrity
Morphological assessment
Purity
Size
Lentiviral vectors
Lentiviral vectors serve as versatile tools in genetic engineering and gene therapy. The transduction efficiency of these vectors relies on the number of mature lentiviral particles; particles with a membrane decorated with glycoproteins, and a capsid c...